Glossary
sensitivity
For a medical test, the share of the people who genuinely have the disease that the test correctly identifies. No test reaches 100 percent, because some cases are always missed.
Every test that looks for a disease can fail in two directions. It can miss someone who has the disease, or flag someone who does not. Sensitivity measures the first kind of failure: the proportion of people who genuinely have the condition that the test correctly picks up. The National Cancer Institute puts it as how well a test detects a disease in the people who actually have it, and notes that no test reaches 100 percent, because some people with the disease will always come back negative.
In a screening programme the figure answers a blunt question: of the women who had breast cancer at the time of their screen, how many did the screen find? A higher sensitivity means fewer cancers left to surface between screening rounds. In the MASAI trial, the first randomised controlled trial of artificial intelligence inside a national mammography programme, sensitivity was 80.5 percent in the group screened with AI support and 73.8 percent in the group read the standard way, a difference the trial reported as statistically significant. Specificity, the matching measure for the other kind of failure, was 98.5 percent in both groups.
Sources
- National Cancer Institute, Sensitivity, NCI Dictionary of Cancer Terms Primary
- The Lancet, Interval cancer, sensitivity, and specificity comparing AI-supported mammography screening with standard double reading without AI in the MASAI study
Checked 28 July 2026